Table 1 Demographic and clinical characteristics of the training and internal validation sets
Variables | Total (N = 71,979) | Training set (N = 50,385) | Internal validation set (N = 21,594) | P values |
|---|---|---|---|---|
Age (IQR, year) | 63.00(51.00,72.00) | 63.00(51.00,72.00) | 63.00(51.00,72.00) | 0.695 |
Sex (n, %) | 0.117 | |||
Female | 39,051(54.25) | 27,432(54.44) | 11,619(53.81) | |
Male | 32,928(45.75) | 22,953(45.56) | 9975(46.19) | |
Insurance type (n, %) | 0.567 | |||
Full self-pay | 6798(9.44) | 4797(9.52) | 2001(9.27) | |
UEMI | 16,887(23.46) | 11,859(23.54) | 5028(23.28) | |
URMI | 45,347(63.00) | 31,671(62.86) | 13,676(63.33) | |
Other insurance | 2947(4.10) | 2058(4.08) | 889(4.12) | |
ACCI score (n, %) | 0.020 | |||
0–4 | 28,730(39.92) | 20,111(39.92) | 8619(39.91) | |
5–7 | 30,305(42.10) | 21,335(42.34) | 8970(41.54) | |
> 7 | 12,944(17.98) | 8939(17.74) | 4005(18.55) | |
Hypertension (n, %) | 0.532 | |||
Yes | 34,910(48.50) | 24,398(48.42) | 10,512(48.68) | |
No | 37,069(51.50) | 25,987(51.58) | 11,082(51.32) | |
CHD (n, %) | 0.273 | |||
Yes | 14,896(20.69) | 10,372(20.59) | 4524(20.95) | |
No | 57,083(79.31) | 40,013(79.41) | 17,070(79.05) | |
CI (n, %) | 0.461 | |||
Yes | 8514(11.83) | 5930(11.77) | 2584(11.97) | |
No | 63,465(88.17) | 44,455(88.23) | 19,010(88.03) | |
Hyperlipidemia (n, %) | 0.901 | |||
Yes | 9914(13.77) | 6934(13.76) | 2980(13.80) | |
No | 62,065(86.23) | 43,451(86.24) | 18,614(86.20) | |
Antihypertensive drug use (n, %) | 0.003 | |||
Yes | 31,618(43.93) | 21,950(43.56) | 9668(44.77) | |
No | 40,361(56.07) | 28,435(56.44) | 11,926(55.23) | |
Statins use (n, %) | 0.057 | |||
Yes | 26,279(36.51) | 18,282(36.28) | 7997(37.03) | |
No | 45,700(63.49) | 32,103(63.72) | 13,597(62.97) | |
Antiplatelet and anticoagulant use (n, %) | 0.051 | |||
Yes | 28,920(40.18) | 20,126(39.94) | 8794(40.72) | |
No | 43,059(59.82) | 30,259(60.06) | 12,800(59.28) | |
PSH (n, %) | 0.530 | |||
Yes | 37,366(51.91) | 26,117(51.83) | 11,249(52.09) | |
No | 34,613(48.09) | 24,268(48.17) | 10,345(47.91) | |
PMH (n, %) | 0.671 | |||
Yes | 57,451(79.82) | 40,194(79.77) | 17,257(79.92) | |
No | 14,528(20.18) | 10,191(20.23) | 4337(20.08) | |
Smoking history (n, %) | 0.264 | |||
Yes | 21,492(29.86) | 14,981(29.73) | 6511(30.15) | |
No | 50,487(70.14) | 35,404(70.27) | 15,083(69.85) | |
Drinking history (n, %) | 0.401 | |||
Yes | 18,225(25.32) | 12,712(25.23) | 5513(25.53) | |
No | 53,754(74.68) | 37,673(74.77) | 16,081(74.47) | |
SBP (IQR, mmHg) | 132.00(120.00,146.00) | 132.00(120.00,146.00) | 131.00(120.00,146.00) | 0.262 |
DBP (IQR, mmHg) | 78.00(70.00,86.00) | 78.00(70.00,86.00) | 78.00(70.00,86.00) | 0.387 |
Pulse (IQR, bpm) | 80.00(74.00,90.00) | 80.00(75.00,90.00) | 80.00(74.00,90.00) | 0.716 |
AST (IQR, IU/L) | 20.00(16.00,26.20) | 20.00(16.00,26.30) | 20.00(16.00,26.10) | 0.899 |
ALT (IQR, IU/L) | 19.00(13.00,29.00) | 19.00(13.00,29.00) | 19.00(13.00,29.00) | 0.836 |
TGs (IQR, mmol/l) | 1.56(1.10,2.34) | 1.57(1.10,2.344) | 1.55(1.10,2.33) | 0.135 |
NLR (IQR) | 2.95(1.99,4.69) | 2.95(1.99,4.67) | 2.97(1.99,4.72) | 0.627 |
PLR (IQR) | 121.15(90.27,166.06) | 121.12(90.23,165.96) | 121.28(90.32,166.35) | 0.736 |
LMR (IQR) | 3.81(2.57,5.42) | 3.82(2.58,5.43) | 3.79(2.56,5.39) | 0.085 |
NPAR (IQR, ml/g) | 16.74(14.26,20.00) | 16.73(14.25,20.00) | 16.75(14.29,20.00) | 0.523 |
CREA (IQR, umol/l) | 64.60(52.10,81.90) | 64.60(52.10,81.80) | 64.64(52.20,81.99) | 0.393 |
UA (IQR, umol/l) | 324.46(263.70,396.40) | 325.00(263.30,396.60) | 323.22(264.51,395.90) | 0.442 |
LDL-C (IQR, mmol/l) | 2.45(1.86,3.07) | 2.44(1.86,3.07) | 2.45(1.85,3.07) | 0.741 |
HDL-C (IQR, mmol/l) | 1.10(0.92,1.33) | 1.10(0.92,1.33) | 1.10(0.92,1.33) | 0.603 |
FG (IQR, mmol/l) | 7.48(5.76,10.61) | 7.48(5.76,10.60) | 7.48(5.75,10.62) | 0.870 |
GFR (IQR, ml/min) | 97.99(76.59,120.14) | 98.00(76.52,120.17) | 97.95(76.79,119.99) | 0.913 |