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Table 1 Clinical characteristics of all patients (N = 90)

From: Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma

Characteristics

N (%)

Age, median (range), year

62 (38–86)

Sex

 Male

35 (38.9%)

 Female

55 (61.1%)

Clinical stage

 I

9 (10.0%)

 II

41 (45.6%)

 III

35 (38.9%)

 IV

5 (5.6%)

Pathological type

 NM

30 (33.3%)

 ALM

40 (44.4%)

 Othersa

11 (12.2%)

 Unknown

9 (10.0%)

Breslow thickness, mm

 ≤ 1.0

4 (4.4%)

 1.01–2.0

16 (17.8%)

 2.01–4.0

25 (27.8%)

 > 4.0

37 (41.1%)

 Unknown

8 (8.9%)

Primary site

 Hand

11 (12.2%)

 Foot

79 (87.8%)

Ulceration status

 Yes

56 (62.2%)

 No

33 (36.7%)

 Unknown

1 (1.1%)

Treatment

 Yes

66 (73.3%)

 No

24 (26.7%)

Mutation statusb

 BRAFm

12 (14.5%)

 NRASm

10 (12.0%)

 KITm

14 (16.9%)

 BRAFw&NRASw&KITw

44 (53.0%)

Survival

 Alive

54 (60.0%)

 Dead

36 (40.0%)

  1. ALM, acral lentiginous melanoma; NM, nodular melanoma; m, mutation; w, wide type
  2. aOthers include 10 cases of superficial spreading melanoma and 1 case of lentigo maligna melanoma
  3. bMutation status was determined according to the 83 NGS-positive patients included in the analysis