Fig. 3

Tumor microenvironment heterogeneity measured by HiTIMED impacts 5-year survival in cancer patients. Kaplan–Meier survival curves with statistically significant hazard ratios from Cox proportion hazard models with age, gender, tumor stage, tumor proportion, and other cell-type proportions adjusted by comparing survival in higher than median value (High) to lower than or equal to median group (Low) for B memory, CD8T memory, dendritic cell, Tregs, epithelial, endothelial, and stromal cells in pan-cancer survival analyses