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Table 3 Predictive performance evaluation of pEV-microRNA signature in discovery and validation cohorts

From: A novel microRNA signature for the detection of melanoma by liquid biopsy

Metrics

Discovery cohort

External validation cohort (GSE20994)

Accuracy

1.00

0.81

Sensitivity

1.00

1.00

Specificity

1.00

0.50

Positive Prediction Rate

1.00

0.76

Negative Prediction Rate

1.00

1.00

AUC ROC (95% CI)

1.00 (1.00, 1.00)

0.94 (0.88, 0.99)

AUC PR (95% CI)

1.00 (1.00, 1.00)

0.96 (0.96, 0.96)