Table 1 Comparison of the basic characteristics between the control (n = 474,927) and AD groups (n = 886)
Characteristics | Control group | AD group | P-adjusted |
|---|---|---|---|
Age (Median, IQR) | 58 (50,63) | 66 (62,68) |  < 0.001 |
TDI (Median, IQR) | −2.2 (−3.7,0.5) | −2 (−3.6,1.1) | 0.0693 |
Sex (n, %) |  |  |  < 0.001 |
 Female | 257,988 (54.3) | 431 (48.6) |  |
 Male | 216,939 (45.7) | 455 (51.4) |  |
Ethnicity (n, %) |  |  |  < 0.01 |
 White people | 432,898 (91.2) | 820 (92.6) |  |
 Mixed people | 17,394 (3.7) | 40 (4.5) |  |
 Other people | 24,635 (5.2) | 26 (2.9) |  |
 Education (n, %) |  |  |  < 0.001 |
 College/University | 155,879 (32.8) | 168 (19) |  |
 Other | 319,048 (67.2) | 718 (81) |  |
Smoking (n, %) |  |  |  < 0.001 |
 Never | 260,085 (54.8) | 422 (47.6) |  |
 Previous | 165,055 (34.8) | 381 (43) |  |
 Current | 49,787 (10.5) | 83 (9.4) |  |
Alcohol (n, %) |  |  |  < 0.001 |
 Never | 20,271 (4.3) | 77 (8.7) |  |
 Previous | 16,833 (3.5) | 66 (7.4) |  |
 Current | 437,823 (92.2) | 743 (83.9) |  |
Myocardial infarction (n, %) | |||
 No | 455,682 (95.9) | 776 (87.6) |  < 0.001 |
 Yes | 19,245 (4.1) | 110 (12.4) |  |
Stroke (n, %) |  |  |  < 0.001 |
 No | 462,880 (97.5) | 787 (88.8) |  |
 Yes | 12,047 (2.5) | 99 (11.2) |  |
Diabetes (n, %) |  |  |  < 0.001 |
 No | 470,331 (99) | 855 (96.5) |  |
 Yes | 4596 (1) | 31 (3.5) |  |
Hypertension (n, %) |  |  |  < 0.001 |
 No | 329,896 (69.5) | 379 (42.8) |  |
 Yes | 145,031 (30.5) | 507 (57.2) |  |
BMI (Median, IQR) | 26.7 (24.1,29.9) | 26.6 (23.9,29.4) | 0.142 |