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Table 2 Association of serum TMAO with type 2 diabetes risk

From: Serum trimethylamine-N-oxide is associated with incident type 2 diabetes in middle-aged and older adults: a prospective cohort study

 

Tertiles of serum TMAO

P-trend

T1 (n = 696)

T2 (n = 696)

T3 (n = 696)

Median, μmol/L

0.66

1.39

4.05

 

Case, n

67

90

97

 

Person years

5474

5420

5319

 

Model 1a

1.00 (Ref)

1.32 (0.96–1.82)

1.47 (1.08–2.01)

0.033

Model 2b

1.00 (Ref)

1.17 (0.84–1.61)

1.42 (1.03–1.96)

0.031

  1. TMAO trimethylamine-N-oxide; Ref, reference
  2. P for trend was calculated by treating the median values of serum TMAO levels in tertiles as continuous values in Cox proportional hazard models
  3. aModel 1: adjusted for age and sex
  4. bModel 2: adjusted for model 1 plus household income, smoking status, alcohol drinking, tea drinking, hypertension, WHR, physical activity, intakes of total energy, egg, red and processed meat, fish and shellfish, serum levels of TG, HDL-C and fasting glucose