Fig. 2

Development of the CD34⁺CD117^dim population signature (117DPS model). a One thousand bootstrap replicates were obtained by LASSO regression analysis for variable selection. The optimal value for the λ parameter was determined by the minimum criteria and 1-SE criteria. b LASSO coefficients of the CD34⁺CD117^dim-related genes in the training cohort (GEO: GSE37642-GPL96). Each curve represents one gene. c Forest plot of a multivariate analysis of the six genes included in the 117DPS model using the GSE37642-GPL96 dataset. HR hazard ratio; CI confidence interval. *P < 0.05; **P < 0.01; ***P < 0.001