Sex hormones and physical function among the Chinese oldest-old and centenarian women

Table 4 Comparison of characteristics between participants with physical normality or decline in all the participants

Variables	Oldest-old women			Centenarian women			All
Variables	Physical decline^a (N = 117)	Physical normality^a (N = 351)	P	Physical decline^a (N = 560)	Physical normality^a (N = 198)	P	Physical decline^a (N = 677)	Physical normality^a (N = 549)	P
Age (year)^b	87.0 (83.0, 91.0)	84.0 (82.0, 88.0)	< 0.001	102.0 (101.0, 104.0)	102.0 (101.0, 104.0)	0.637	102.0 (100.0, 104.0)	88.0 (83.0, 101.0)	< 0.001
Han ethnicity, n (%)^c	97 (82.9)	317 (90.3)	0.030	494 (88.2)	178 (89.9)	0.521	591 (87.3)	495 (90.2)	0.117
Illiteracy, n (%)^c	107 (91.5)	325 (92.6)	0.689	543 (97.0)	189 (95.5)	0.316	650 (96.0)	514 (93.6)	0.058
Smoker, n (%)^c	4 (3.4)	9 (2.6)	0.871	37 (6.6)	15 (7.6)	0.643	41 (6.1)	24 (4.4)	0.191
Drinker, n (%)^c	22 (18.8)	58 (16.5)	0.571	78 (13.9)	25 (12.6)	0.646	100 (14.8)	83 (15.1)	0.865
E2 (pmol/L)^b	18.4 (18.4, 36.9)	18.4 (18.4, 36.9)	0.276	36.9 (18.4, 61.5)	18.5 (18.4, 38.7)	< 0.001	34.0 (18.4, 55.5)	18.4 (18.4, 36.9)	< 0.001
T (nmol/L)^b	0.4 (0.2, 0.9)	0.4 (0.2, 0.9)	0.973	0.4 (0.2, 0.8)	0.3 (0.2, 0.6)	0.001	0.4 (0.2, 0.8)	0.4 (0.2, 0.8)	0.168
E2/T^b	59.4 (25.7, 172.2)	55.8 (23.0, 141.5)	0.620	94.5 (48.4, 204.4)	102.2 (51.5, 204.4)	0.894	86.3 (42.7, 204.4)	68.1 (31.2, 184.2)	< 0.001
FSH (mIU/mL)^b	83.1 (69.1, 103.2)	82.3 (64.0, 98.6)	0.122	82.3 (62.2, 102.2)	78.3 (59.2, 96.2)	0.035	82.3 (63.4, 102.3)	82.3 (61.8, 97.3)	0.084
LH (mIU/mL)^b	38.1 (30.2, 46.2)	35.5 (27.5, 41.6)	0.002	37.5 (29.4, 47.8)	33.7 (26.2, 43.1)	0.001	37.5 (29.6, 47.6)	34.9 (26.9, 42.3)	< 0.001
ADL^b	85 (70, 90)	100 (100, 100)	< 0.001	75 (50, 85)	95 (95, 100)	< 0.001	75.0 (55, 85)	100.0 (95, 100)	< 0.001

ADL activity of daily living; E2 estradiol; E2/T estradiol/testosterone; FSH follicle-stimulating hormone; LH luteinizing hormone; T testosterone
^aPhysical normality was defined by a total score of ADL ≥ 95 points, and physical decline was defined by a total score of ADL < 95 points
^bContinuous variables with skewed distributions were presented with medians (interquartile ranges) and compared with Mann–Whitney U tests
^cCategorical variables were presented with numbers (percentages) and compared with Chi-square tests

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