Skip to main content

Table 2 Univariable and multivariable Cox regression analysis of the novel immune checkpoints-based signature and overall survival in TCGA cohort

From: A novel immune checkpoints-based signature to predict prognosis and response to immunotherapy in lung adenocarcinoma

 

Univariable analysis

Multivariable analysis

Variable

HR

95%CI

P value

HR

95%CI

P value

Age

 ≥ 60 or < 60

1.0855

0.7524–1.5658

0.6609

1.3874

0.9432–2.0410

0.0963

Sex

 Male or female

1.1320

0.8254–1.5525

0.4419

0.9599

0.6849–1.3455

0.8125

Smoking history

 Yes or no

0.9332

0.6030–1.4444

0.7565

1.04711

0.6408–1.7110

0.8542

T stage

 1, 2, 3 or 4

1.9309

1.4885–2.5049

 < 0.0001

1.1945

0.9648–1.4790

0.1029

Lymphatic metastasis

 Yes or no

1.0001

0.8281–1.2096

 < 0.0001

1.2839

0.9116–1.8082

0.1526

TNM stage

 I, II, III or IV

1.5867

1.3685–1.8396

 < 0.0001

1.3638

1.1063–1.6811

0.0037

EGFR status

 MUT or WT

1.4752

0.9718–2.2394

0.0679

1.4295

0.9034–2.2620

0.1270

KRAS status

 MUT or WT

1.2462

0.8864–1.7521

0.2054

1.3121

0.9148–1.8820

0.1397

Risk score

 High or low

2.5718

1.6286–4.0612

 < 0.0001

2.5167

1.5408–4.1107

0.0002

  1. HR hazard ratio, CI confidence interval
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us