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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis

Fig. 4

Similar regeneration efficiency in WT and Hspa4-KO muscles. A Morphological assessment of injured tibialis anterior muscles was performed via H&E staining post-injury. B Graph illustrating the distribution of regenerating myofiber size frequency. C Average CSA of regenerating fibers containing centralized nuclei. D–F Real time PCR analyses of the myogenic transcription factors in injured muscles. Data are expressed as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs. corresponding vehicle, one-way ANOVA with Bonferroni post-test (n = 3–4mice/ time point/ genotype)

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