Fig. 3

EVs are abundant in peripheral blood of ALL patients and can be internalized by BALL-1 cells. A Expression column diagram of miRNA-181b-5p in EVs from different tissues, with the X-axis representing cell type and the Y-axis representing expression RPM; B protein expression of surface markers of EVs from healthy people and ALL patients; C the expression level of miRNA-181b-5p in EVs from healthy people and ALL patients; D the internalization of EVs by BALL-1 cells; E the EVs uptake rate was calculated by flow cytometry; *p < 0.05