Fig. 5

Metabolites and lipids correlated with RA disease activity. Boxplots (A) and ROC analysis (B) of seven metabolites and lipids with differential levels among normal control group (NCs) and RA with low disease activity (R-L), moderate disease activity (MOD) and high disease activity (HIGH). # p < 0.05 versus NCs group, *p < 0.05 versus R-L group. Data are presented as mean ± SEM, and analyzed by Wilcoxon−Mann U test with FDR control