Fig. 4

Association between the inflammation-immune activity and aberrant metabolism. A Serum metabolites and lipids levels were associated with the risk for RA according to relative peak intensity from untargeted mass spectrometry analyses of subjects (N = 325). B RA-associated metabolite and lipids in cellular metabolic pathways. Upregulated metabolites or lipids were colored in red and downregulated metabolites or lipids were colored in green