Characteristics | No mutation | LDLR (−) | LDLR (+) |
---|
Model 1 ORs | 1 (Reference) | 0.827 (0.222–3.077) | 3.978 (1.980–7.989) |
p value |  | 0.776 |  < 0.001 |
Model 2 ORs | 1 (Reference) | 0.810 (0.217–3.021) | 4.193 (2.060–8.534) |
p value |  | 0.754 |  < 0.001 |
Model 3 ORs | 1 (Reference) | 0.919 (0.190–4.451) | 3.493 (1.442–8.465) |
p value | Â | 0.917 | 0.006 |
- Model 1 unadjusted, model 2 age- and sex- adjusted, model 3 fully adjusted for age, sex, BMI, CAD, smoking, hypertension, DM, family history of CAD, uncontrolled LDL-C levels, lipid-lowering therapy, total cholesterol year score and LDL cholesterol year score. Bold values indicate statistical significance
- LDLR: low-density lipoprotein receptor; LDLR (−): LDLR negative mutation; LDLR (+): LDLR positive mutation; OR: odds ratio; BMI: body mass index; CAD: coronary artery disease; DM: diabetes mellitus