Development and validation of a score to predict mortality in ICU patients with sepsis: a multicenter retrospective study

Table 5 Net benefit of using the POSMI score, APACHE IV and SOFA compared to treating sepsis assuming all of them will die during the ICU stay

Threshold probability	Net benefit				Advantage of using A-SIMP score
Threshold probability	Treat all	POSMI score	APACHE IV	SOFA	Difference in net benefit^a
0.01	0.924	0.93	0.925	0.924	0.006
0.02	0.847	0.863	0.851	0.847	0.016
0.03	0.769	0.813	0.777	0.769	0.044
0.04	0.689	0.777	0.709	0.689	0.088
0.05	0.607	0.731	0.665	0.608	0.124
0.1	0.169	0.553	0.474	0.409	0.384
0.15	− 0.319	0.433	0.321	0.296	0.752
0.2	− 0.869	0.328	0.222	0.195	1.197
0.25	− 1.492	0.257	0.149	0.138	1.749
0.3	− 2.203	0.223	0.103	0.103	2.426
0.35	− 3.025	0.182	0.076	0.089	3.207
0.4	− 3.983	0.162	0.064	0.067	4.145
0.45	− 5.116	0.139	0.04	0.065	5.255
0.5	− 6.475	0.114	0.024	0.026	6.589
0.55	− 8.136	0.096	0.02	0.013	8.232
0.6	− 10.212	0.059	− 0.005	0.004	10.271
0.65	− 12.881	0.047	− 0.004	0.01	12.928
0.7	− 16.441	0.013	− 0.011	0.005	16.454
0.75	− 21.424	0.03	0.006	0.01	21.454
0.8	− 28.898	0.004	0.004	0.008	28.902

ISSN: 1479-5876