Skip to main content

Table 1 PDX establishment success by condition and patient characteristics

From: Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients

Patient

Implantation Conditions (Growth Observed)

Patient data

Fresh

Cryopreserved

HPV Status

Primary tumor type

Origin of tissue

Diagnosis

Sex

Age

Tobacco history

Metastatic

Original staging

UW-SCC-97

Yes

Yes

−

Skin

Lymph node

Melanoma

F

71

No

Yes

NA

UW-SCC-100

No

No

Unknown

Tongue

Tongue

Squamous cell carcinoma

M

50

No

No

pT2N2b

UW-SCC-102

No

No

+

Tongue

Tongue

Squamous cell carcinoma

M

60

Yes

No

pT2N1

UW-SCC-103

No

No

−

Floor of Mouth

Floor of Mouth

Squamous cell carcinoma

M

57

Yes

No

pT4aN0

UW-SCC-130

Yes

Yes

−

Skin

Parotid gland

Metastatic squamous cell carcinoma

M

85

No

Yes

TxN2bM0

UW-SCC-133

Yes

Yes

+

Base of Tongue

Tongue

Recurrent invasive squamous cell carcinoma

M

69

Yes

No

pT4NxMx

UW-SCC-136

Yes

Yes

−

Hypopharynx

Hypopharynx

Squamous cell carcinoma

M

59

Yes

No

T2N1M0

UW-SCC-137

Yes

Noa

−

Nasal Cavity

Ethmoid Sinus

Poorly differentiated carcinoma

M

77

No

No

pT4b

UW-SCC-148

Yes

Yes

−

Unknown primary

Lymph Node

Poorly differentiated squamous cell carcinoma

M

60

Yes

Yes

TxN3M0

UW-SCC-149

Yes

Yes

−

Skin

Lymph node

Squamous cell carcinoma/spindle cell carcinoma

F

71

Yes

Yes

pT2NxMx

  1. aNo invasive SCC developed, cryopreserved tissue developed a lymphoproliferative mass