Fig. 5

Detection of serum IL-12 and IFN -γ levels. The levels of IL-12 differed significantly among the groups (P < 0.05). The highest IL-12 levels were noted in the FYD + IL-12 + BMSC group (P < 0.05). In particular, significant differences were noted between the IL-12 + BMSC and FYD groups and between the IL-12 + BMSC and FYD + IL-12 + BMSC groups (P < 0.05). In addition, significant differences were noted with regard to IFN-γ levels (P < 0.05) among the groups, with the highest levels observed in the FYD + IL-12 + BMSC group (P < 0.05), as shown in a, b. n = 5, ^#P < 0.05: Compared with the model group, ^*P < 0.05; compared with the model group. One-way analysis of variance was performed (IL-12: F = 1107.69, P = 0.00; IFN-γ: F = 5456.68, P = 0.00). The q-test was used to compare the two groups and significant differences were noted between the two groups (P < 0.05). BMSCs, bone marrow mesenchymal stem cells; IL-12 + BMSC, IL12-lentiviral-transfected BMSC; FYD, FuzhengYiliu decoction; FYD + IL-12 + BMSC group, FYD treatment in IL-12 lentiviral-transfected BMSC group