Expression and prognostic roles of PRDXs gene family in hepatocellular carcinoma

Table 2 The type and frequency of PRDX gene family neighbor gene alterations in hepatocellular carcinoma (cBioPortal)

Genes	Amplification	Homozygous deletion	Up-regulation	Down-regulation	Mutation	Total alteration
AR			0.069	0	0.028	0.094
CDK1	0.006		0.064	0	0	0.069
EPX
GPX1
GSS
GSTP1	0.025		0.025	0	0.006	0.053
KLK3	0.008		0.036	0	0	0.044
LCK	0.003	0.006	0.033	0	0.011	0.053
LPO
MAPK1	0.003	0.003	0.047	0.069	0.008	0.131
MAX		0.003	0.053	0.058	0	0.111
MYC	0.178	0.003	0	0	0.006	0.186
PBK		0.058	0.053	0	0.003	0.114
PRDX1	0.003		0.064	0.003	0.003	0.072
PRDX2		0.003	0.081	0.003	0.006	0.092
PRDX3	0.003		0.05	0.053	0.006	0.111
PRDX4
PRDX5		0.003	0.083	0	0	0.086
PRDX6	0.097		0.089	0	0.003	0.175
PXDN
STK4	0.003		0.05	0	0.003	0.056
TXN	0.003		0.058	0	0.003	0.061
TXN2	0.008		0.083	0.008	0.008	0.106
TXNDC12
TXNRD1	0.008		0.072	0	0	0.081
TXNRD2	0.006	0.003	0.047	0	0	0.056
TXNRD3

ISSN: 1479-5876