Table 3 Chea3 transcription factor enrichment analysis of the LMWF5A-reduced cytokine signature
Rank | Transcription factor | Mean rank | Overlapping genes |
|---|---|---|---|
Sorted by mean rank | |||
1 | Basic leucine zipper transcription factor, ATF-like 3 (BATF3) | 10.33 | 4 |
2 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) | 17.25 | 5 |
3 | Ets variant 3-like (ETV3L) | 17.33 | 3 |
4 | Interferon regulatory factor 8 (IRF8) | 24 | 3 |
5 | v-rel avian reticuloendotheliosis viral oncogene homolog (REL) | 25 | 3 |
6 | Zinc finger protein 267 (ZNF267) | 32 | 3 |
7 | Signal transducer and activator of transcription 1, 91 kDa (STAT1) | 33.83 | 5 |
8 | Musculin (MSC) | 38 | 3 |
9 | Basic leucine zipper transcription factor, ATF-like (BATF) | 38.2 | 5 |
10 | Early growth response 2 (EGR2) | 40.33 | 3 |
Sorted by overlapping genes | |||
93 | v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) | 252.7 | 7 |
409 | Jun proto-oncogene (JUN) | 530 | 5 |
354 | Estrogen receptor 1 (ESR1) | 490.8 | 5 |
2 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) | 17.75 | 5 |
7 | Signal transducer and activator of transcription 1, 91 kDa (STAT1) | 34.67 | 5 |
28 | Zinc finger, BED-type containing 2 (ZBED2) | 143.7 | 5 |
67 | v-rel avian reticuloendotheliosis viral oncogene homolog B (RELB) | 215 | 5 |
95 | Ets variant 7 (ETV7) | 257.3 | 5 |
242 | SP140 nuclear body protein (SP140) | 412 | 5 |
314 | Basic leucine zipper transcription factor, ATF-like 2 (BATF2) | 463.3 | 5 |