Fig. 6

The role SYNE3 played in tumor microenvironment. a Immune infiltration level associated with SYNE3 in HNSC, KIRC and LUAD analyzed in TIMER. b The relationship between immune cell infiltration and lung adenocarcinoma prognosis, higher infiltration level of B cell and dentritic cell were significantly associated with better clinical outcome of LUAD. c Higher SYNE3 expression was correlated with longer OS of patients with lung adenocarcinoma. d SYNE3 expression was significantly downregulated in LUAD compared with that in normal lung tissues. e GSEA analysis grouped by SYNE3 expression level. f The correlation between SYNE3 expression and expression of B cell and dentritic cell based on GEPIA database