Fig. 1

The percentage of cDCs and mDCs in the lungs of ALI mice and the degree of pathological damage at different times after intratracheal injection of LPS. a, b The percentage of cDCs changed with time after intratracheal LPS injection in ALI mice. c, d Representative tissue sections of lung tissue (hematoxylin and eosin staining; magnification, ×200) and pathological lung injury scores from 0 to 24 h. e, f Expression of MHCII and CD86 in cDCs in the mouse lung cells from 0 to 24 h after intratracheal LPS injection. g–i The correlation between the percentage of cDCs, MHCII⁺ cDCs and CD86⁺ cDCs and pathological scores was analyzed by Pearson correlation coefficient. The data are presented as the mean ± SD. *p < 0.05 vs. the control group; n = 6 per group