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Table 1 Correlations of sCLU and β-catenin expressions with clinical factors

From: Secretory clusterin promotes hepatocellular carcinoma progression by facilitating cancer stem cell properties via AKT/GSK-3β/β-catenin axis

Parameters

n

sCLU, n (%)

P

β-Catenin, n (%)

P

Coexpression, n (%)

P

AFP(µg/L)

  

0.781

 

0.343

 

0.238

 < 50

36

28 (77.78)

 

18 (50.00)

 

16 (44.44)

 

 ≥ 50

36

27 (75.00)

 

22 (61.11)

 

21 (58.33)

 

Portal vein invasion

  

0.745

 

0.792

 

0.749

 With

7

5 (71.43)

 

4 (57.14)

 

4 (57.14)

 

 Without

65

50 (76.92)

 

36 (55.38)

 

33 (50.77)

 

HBsAg

  

0.429

 

0.482

 

0.768

 Positive

28

20 (71.43)

 

17 (60.71)

 

15 (53.57)

 

 Negative

44

35 (79.55)

 

23 (52.27)

 

22 (50.00)

 

Tumor size (cm)

  

0.137

 

0.570

 

0.207

 < 5

44

31 (70.45)

 

23 (52.27)

 

20 (45.45)

 

 ≥ 5

28

24 (85.71)

 

17 (60.71)

 

17 (60.71)

 

Liver cirrhosis

  

0.262

 

0.273

 

0.220

 With

54

43 (79.63)

 

32 (59.26)

 

30 (55.56)

 

 Without

18

12 (66.67)

 

8 (44.44)

 

7 (38.89)

 

Metastasis

  

0.012

 

< 0.001

 

< 0.001

 With

22

21 (95.45)

 

19 (86.36)

 

19 (86.36)

 

 Without

50

34 (68.00)

 

21 (42.00)

 

18 (36.00)

 

Differentiation

  

0.235

 

0.228

 

0.115

 Poor

16

14 (87.50)

 

11 (68.75)

 

11 (68.75)

 

 Others

56

41 (73.21)

 

29 (51.78)

 

26 (46.43)

 

Multifocal

  

0.235

5.500

0.019

 

0.032

 Yes

16

14 (87.50)

 

13 (81.25)

 

12 (75.00)

 

 No

56

41 (73.21)

 

27 (48.21)

 

25 (44.64)

 

TNM stage

  

< 0.001

 

0.001

 

< 0.001

 I and II

43

26 (60.47)

 

17 (39.53)

 

13 (30.23)

 

 III and IV

29

29 (100.00)

 

23 (79.31)

 

24 (82.76)

 
  1. AFP α-fetoprotein, TNM tumor-node-metastasis, sCLU secretory clusterin
  2. Italics, P < 0.05