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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Administration of losartan preserves cardiomyocyte size and prevents myocardial dysfunction in tail-suspended mice by inhibiting p47phox phosphorylation, NADPH oxidase activation and MuRF1 expression

Fig. 1

Tail-suspension reduces apelin/apelin receptor expression and increases angiotensin-II production in mouse hearts. After tail-suspension (TS), cDNA microarray was performed to determine differential expression of genes in mouse hearts. a Heat map of differential gene expression. b, c The mRNA levels of apelin and apelin receptor relative to Gapdh were analyzed by real-time RT-PCR. d Angiotensin-II production was measured in heart lysates. Data are mean ± SD, n = 6 in each group. *P < 0.05

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Journal of Translational Medicine

ISSN: 1479-5876

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