Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion

Table 2 Plasma levels of each biomarker in different groups

Proteins	Healthy controls (n = 33)	Patients with AIS due to non-LVO (n = 33)	Patients with AIS due to LVO (n = 33)	P value	P^a value	P^b value	P^c value
IGF2	0.86 ± 0.24	0.90 ± 0.50	1.19 ± 0.42	0.001	0.948	0.001	0.017
LYVE1	0.97 ± 0.50	0.99 ± 0.49	1.61 ± 0.56	< 0.001	0.998	< 0.001	< 0.001
PPBP	0.98 ± 0.37	1.23 ± 0.55	1.58 ± 0.78	< 0.001	0.081	0.001	0.045
THBS1	0.43 ± 0.26	0.62 ± 0.29	1.13 ± 0.88	< 0.001	0.030	< 0.001	0.010

Data are shown as mean ± SD. One-way analysis of variance (ANOVA) with Dunnett’s post hoc test
AIS acute ischemic stroke, LVO large vessel occlusion
^aPatients with AIS due to non-LVO versus healthy controls
^bPatients with AIS due to LVO versus healthy controls
^cPatients with AIS due to LVO versus patients with AIS due to non-LVO

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