| Ctrl-WT | Ctrl-FNDC5−/− | HFD-WT | HFD-FNDC5−/− |
---|---|---|---|---|
IVSd (mm) | 0.7 ± 0.02 | 0.74 ± 0.02 | 0.75 ± 0.01†| 0.82 ± 0.02*†|
IVSs (mm) | 1.07 ± 0.02 | 1.1 ± 0.03 | 1.19 ± 0.02†| 1.20 ± 0.02†|
LVIDd (mm) | 4.05 ± 0.11 | 4.0 ± 0.11 | 3.98 ± 0.14 | 4.01 ± 0.1 |
LVIDs (mm) | 3.16 ± 0.13 | 2.98 ± 0.1 | 2.73 ± 0.12†| 2.84 ± 0.08 |
LVPWd (mm) | 0.72 ± 0.02 | 0.74 ± 0.03 | 0.77 ± 0.02 | 0.85 ± 0.02*†|
LVPWs (mm) | 1.17 ± 0.02 | 1.18 ± 0.03 | 1.25 ± 0.02†| 1.24 ± 0.03 |
LVEF (%) | 59.4 ± 2 | 57.3 ± 1.6 | 48.1 ± 1.7†| 49.7 ± 1.7†|
LVFS (%) | 32.2 ± 1.3 | 30.3 ± 1.2 | 25.2 ± 1.2†| 24.7 ± 1.5†|