Fig. 1
From: Malignant transformation of oral leukoplakia is associated with macrophage polarization
Typical expression patterns of macrophage markers in transforming OLP, non-transforming OLP, OSCC and healthy mucosa. Representative micrographs show the typical expression pattern of macrophage markers (CD68, CD163, CD11c) in transforming OLP (group 1; first row), non-transforming OLP (group 2; second row), OSCC (group 3; third row) and healthy oral mucosa (group 4; fourth row). All micrographs are given in high-power magnification (×40 magnification) and panoramic magnification (×8 magnification). CD68 (left column), CD163 (middle column) and CD11c (right column) show a cytoplasmatic staining with accentuation of the plasma membrane. The first micrograph (transforming OLP, CD68) includes a red line showing the separation between the epithelial and the subepithelial compartment. OLP oral leukoplakia, OSCC oral squamous cell carcinoma