Identification of potential miRNA–mRNA regulatory network contributing to pathogenesis of HBV-related HCC

Table 1 Common (GEO2R and R-limma) differentially expressed miRNAs (DE-miRNAs) between HBV-related HCC tumor versus non-tumor liver tissue

Upregulated DE-miRNA	log₂FC	t	B	P value
hsa-miR-25-3p	1.86	5.2	− 0.0946	7.03E−04
hsa-miR-501-3p	7.01	19.1	8.4883	3.14E−08
hsa-miR-93-5p	1.84	3.66	− 2.2376	5.84E−03
hsa-miR-532-5p	5.83	3.46	− 2.5537	7.99E−03
hsa-miR-106b-5p	2.68	5.37	0.1219	5.67E−04
hsa-miR-21-5p	3.89	6.85	1.8157	1.03E−04
hsa-miR-151-3p	3.38	5.38	0.14	5.57E−04

Downregulated DE-miRNA	log₂FC	t	B	P value
hsa-miR-199a-3p	− 3.06	− 3.85	− 1.9612	4.45E−03
hsa-miR-139-5p	− 3.48	− 5.58	0.3815	4.38E−04
hsa-miR-30a-3p	− 6.24	− 3.93	− 1.8413	3.95E−03
hsa-let-7c-5p	− 2.14	− 3.52	− 2.4572	7.26E−03
hsa-miR-486-5p	− 3.83	− 5.1	− 0.2182	7.95E−04
hsa-miR-125b-5p	− 3.43	− 6.63	1.5818	1.31E−04
hsa-miR-99a-5p	− 2.4	− 3.45	− 2.5639	8.07E−03
hsa-miR-10a-5p	− 1.37	− 3.83	− 1.9874	4.56E−03
hsa-miR-199a-5p	− 2.95	− 6.02	0.899	2.61E−04

ISSN: 1479-5876