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Table 1 Baseline characteristics

From: Real-world use of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers/β-blocks in Chinese patients before acute myocardial infarction occurs: patient characteristics and hospital follow-up

Characteristics

Before PS match

p value

After PS match

p value

AAβ (n = 872)

NO-AAβ (n = 1833)

AAβ (n = 226)

NO-AAβ (n = 452)

Demographic

 Age (years)

68 (58–78)

63 (55–76)

< 0.001

64 (55–77)

66 (55–78)

0.56

 Male sex

582 (66.7)

1336 (72.9)

0.001

155 (68.6)

319 (70.6)

0.60

 BMI (kg/m2)

25.6 (23.4–27.9)

25.0 (22.9–27.4)

0.001

25.4 (23.4–28.0)

25.3 (22.9–27.6)

0.28

Initial presentation

 SBP (mmHg)

133 (122–149)

126 (112–140)

< 0.001

130 (117–144)

130 (118–144)

0.93

 DBP (mmHg)

74 (67–82)

72 (65–80)

< 0.001

74 (67–83)

74 (65–82)

0.50

 Killip class ≥ 2

318 (36.5)

531 (29)

< 0.001

65 (28.8)

130 (28.8)

0.23

Past history

 HT

836 (95.9)

940 (51.4)

< 0.001

191 (84.5)

382 (84.5)

1

 DM

376 (43.1)

550 (30.0)

< 0.001

29 (12.8)

67 (14.8)

0.48

 Dyslipidemia

414 (47.6)

689 (38.2)

< 0.001

78 (34.5)

146 (32.3)

0.56

 Smoking

460 (52.8)

1144 (62.4)

< 0.001

122 (54.0)

262 (58.2)

0.29

 CRF

96 (11)

101 (5.5)

< 0.001

14 (6.19)

23 (5.09)

0.55

 HF

24 (2.78)

11 (0.61)

< 0.001

2 (0.88)

2 (0.44)

0.48

 CAD

459 (52.7)

594 (32.7)

< 0.001

35 (15.5)

71 (15.7)

0.94

 Previous MI

149 (17.1)

172 (9.5)

< 0.001

22 (9.7)

35 (7.8)

0.38

 Previous PCI

219 (25.1)

194 (10.6)

< 0.001

18 (8.0)

17 (3.8)

0.02

 Stroke

188 (21.6)

285 (15.6)

< 0.001

41 (18.1)

81 (17.9)

0.94

Laboratory finding

 TC (mmol/L)

4.10 (3.44–4.78)

4.42 (3.77–5.08)

< 0.001

4.27 (3.61–4.86)

4.42 (3.84–5.04)

0.01

 TG (mmol/L)

1.35 (0.99–1.97)

1.40 (1.0–1.97)

0.287

1.27 (0.99–1.87)

1.38 (0.99–1.96)

0.21

 LDL-C (mmol/L)

2.33 (1.83–2.80)

2.55 (2.07–3.06)

< 0.001

2.41 (1.96–2.93)

2.60 (2.13–3.01)

0.004

 pNT-proBNP (ng/L)

2035 (587–7645)

1637 (557–5475)

0.01

1712 (674–5693)

1701 (587–5598)

0.91

 Scr (μmol/L)

88.3 (75.0–106.8)

83.5 (74.0–96.0)

< 0.001

84.2 (74.4–101.6)

84.5 (75.0–95.7)

0.51

 GFR (mL/min

72.2 (55.2–87.3)

80.5 (64.1–95.1)

< 0.001

74.7 (59.8–89.3)

78.1 (63.6–93.9)

0.14

Hospital course

 STEMI

326 (37.4)

980 (53.5)

< 0.001

113 (50)

258 (57.1)

0.08

 NSTEMI

546 (62.6)

853 (46.5)

< 0.001

113 (50)

194 (42.9)

0.08

 E-PCI

191 (29.7)

534 (36.5)

0.003

53 (29.0)

139 (37.6)

0.046

  1. AAβ ACEI/ARB/β-B, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HT hypertension, DM diabetes mellitus, CRF chronic renal failure, HF heart failure, CAD coronary artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, TC total cholesterol, TG triglyceride, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, NT-proBNP N-terminal pro-brain natriuretic peptide, GFR glomerular filtration rate, STEMI ST-segment elevation AMI, NSTEMI non-ST-segment elevation AMI, E-PCI emergency percutaneous coronary intervention
  2. p values for comparisons between the two groups. Significance level was 0.05