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Table 4 Multivariate adjusted risk estimation of different systolic and diastolic blood pressure and pulse pressure quartiles for CV-mortality in the total population and those with and without anti-hypertensive medication: Tehran Lipid and Glucose study (1999–2014)

From: Blood pressure components and incident cardiovascular disease and mortality events among Iranian adults with chronic kidney disease during over a decade long follow-up: a prospective cohort study

 

BP category

Model 1

Model 2

 

E/N

HR

(95% CI)

p

HR

(95% CI)

p

Total (N = 1232)

SBP < 120

14/367

1.03

(0.47–2.23)

0.95

1.11

(0.51–2.42)

0.79

120 ≤ SBP < 130*

12/224

Ref

  

Ref

  

130 ≤ SBP < 140

13/211

1.14

(0.52–2.49)

0.75

0.92

(0.41–2.05)

0.85

SBP ≥ 140

61/430

2.07

(1.11–3.86)

0.02

2.21

(1.16–4.22)

0.016

DBP < 80

43/544

3.69

(1.46–9.34)

0.006

3.0

(1.17–7.7)

0.022

80 ≤ DBP < 85*

5/242

Ref

  

Ref

  

85 ≤ DBP < 90

17/165

5.13

(1.89–13.9)

0.001

5.48

(2.01–14.92)

0.001

DBP ≥ 90

35/281

6.36

(2.48–16.32)

< 0.001

6.86

(2.66–17.7)

< 0.001

PP < 40*

9/327

Ref

  

Ref

  

40 ≤ PP < 50

19/291

1.69

(0.76–3.76)

0.19

1.58

(0.7–3.54)

0.27

50 ≤ PP < 64

23/307

1.44

(0.68–3.27)

0.31

1.25

(0.57–2.75)

0.58

PP ≥ 64

49/307

2.49

(1.20–5.20)

0.014

2.22

(1.06–4.64)

0.034

  1. Subjects with prevalent CVD were excluded for CV-mortality
  2. Model 1: Adjusted for sex
  3. Model 2: Adjusted for sex, BMI, diabetes, hypercholesterolemia, eGFR, smoking and anti-hypertensive medication (only for the total population). Age was adjusted by considering it as the time-scale
  4. CVD cardiovascular disease, BP blood pressure, SBP systolic blood pressure, DBP diastolic blood pressure, pp pulse pressure, E/N events/N, HR hazard ratio, CI confidence interval
  5. *Reference intervals