Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation?

Table 3 Statistical correlation between LPS serum levels and endometrial Nalp-3 inflammasome expression, anxiety and depression state in women with RPL

	LPS levels		P value
	Normal	Abnormal	P value
Nalp-3 expression [n = 35]
Normal	7 (20%)	1 (2.9%)	< 0.01
Abnormal	8 (22.9%)	19 (54.2%)
Anxiety state (STAI-Y1) [n = 70]
Absent	1 (1.4%)	5 (7.1%)	0.8
Present	18 (25.8%)	46 (65.7%)
Anxiety trait (STAI-Y2) [n = 70]
Absent	1 (1.4%)	15 (21.4%)	< 0.05
Present	15 (21.4%)	39 (55.8%)
Depression state (Zung scale) [n = 70]
Absent	10 (14.3%)	10 (14.3%)	0.6
Present	10 (14.3%)	40 (57.1%)

Results are expressed as percentage (%) of total. LPS lipopolysaccharide. P < 0.05. n number

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