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Table 2 Statistical correlation between abnormal intestinal permeability and circulating levels of LPS, endometrial Nalp-3 inflammasome expression, anxiety and depression state in women with RPL

From: Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation?

 

Intestinal permeability

P value

Normal

Abnormal

LPS serum levels [n = 70]

 Normal

4 (5.7%)

10 (14.3%)

0.8

 Abnormal

5 (7.1%)

51 (72.9%)

 

Abnormal endometrial Nalp-3 expression [n = 35]

 Normal

3 (8.6%)

2 (5.7%)

< 0.01

 Abnormal

4 (11.4%)

26 (74.3%)

 

Anxiety state (STAI-Y1) [n = 70]

 Absent

1 (1.4%)

6 (8.6%)

0.9

 Present

1 (1.4%)

62 (88.6%)

 

Anxiety trait (STAI-Y2) [n = 70]

 Absent

1 (1.4%)

12 (17.2%)

0.3

 Present

1 (1.4%)

56 (80.0%)

 

Depression state (Zung scale) [n = 70]

 Absent

1 (1.4%)

22 (31.4%)

0.6

 Present

1 (1.4%)

46 (65.8%)

 
  1. Results are expressed as percentage (%) of total. LPS lipopolysaccharide. P < 0.05. n number