From: Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease
Uniprot ID | Name | Discovery set | Test set | CVD relevant publications | ||||
---|---|---|---|---|---|---|---|---|
Number of peptides | Cases/controls | Mann–Whitney p-value | Number of peptides | Cases/controls | Mann–Whitney p-value | |||
Q96M60 | Protein FAM227B | 2 | 0.44 | 7.58E−04 | 2 | 0.38 | 8.11E−03 |  |
Q03164 | Histone-lysine N-methyltransferase 2A | 2 | 0.38 | 9.84E−04 | 2 | 0.12 | 8.11E−03 |  |
Q9NVW2 | E3 ubiquitin-protein ligase RLIM | 3 | 2.66 | 4.23E−03 | 4 | 2.46 | 8.11E−03 |  |
O60494 | Cubilin | 2 | 15.19 | 1.18E−03 | 2 | 27.19 | 1.29E−02 |  |
P01023 | Alpha-2-macroglobulin | 64 | 2.37 | 1.27E−03 | 82 | 2.50 | 1.37E−02 | |
Q02880 | DNA topoisomerase 2-beta | 3 | 3.86 | 2.98E−03 | 9 | 3.25 | 1.37E−02 |  |
Q8WWI1 | LIM domain only protein 7 | 2 | 3.26 | 4.23E−03 | 2 | 3.33 | 2.25E−02 | [76] |
O75665 | Oral-facial-digital syndrome 1 protein | 2 | 3.01 | 1.86E−02 | 2 | 3.36 | 2.25E−02 | [77] |
P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 2 | 2.67 | 4.61E−02 | 2 | 5.50 | 3.53E−02 | [78] |
O75445 | Usherin | 2 | 2.50 | 3.35E−03 | 5 | 9.25 | 5.52E−02 |  |
P05546 | Heparin cofactor 2 | 8 | 2.99 | 3.36E−03 | 17 | 3.99 | 5.52E−02 | |
Q8IZU0 | Protein FAM9B | 2 | 2.36 | 3.36E−03 | 2 | 4.14 | 5.52E−02 |  |
A0AUZ9 | KAT8 regulatory NSL complex subunit 1-like protein | 2 | 3.30 | 1.53E−02 | 2 | 2.11 | 5.52E−02 |  |
Q92766 | Ras-responsive element-binding protein 1 | 2 | 2.31 | 3.88E−02 | 2 | 3.35 | 6.73E−02 |  |
Q5TEZ5 | Uncharacterized protein C6orf163 | 4 | 2.13 | 1.25E−02 | 4 | 2.28 | 8.28E−02 |  |
P54317 | Pancreatic lipase-related protein 2 | 2 | 0.01 | 4.51E−03 | 3 | Only in controls | 9.96E−02 |  |
Q9H6S0 | Probable ATP-dependent RNA helicase YTHDC2 | 3 | 5.23 | 4.60E−03 | 6 | 2.31 | 1.21E−01 |  |
P01266 | Thyroglobulin | 3 | 0.33 | 9.90E−03 | 4 | 0.46 | 1.21E−01 |  |
P08185 | Corticosteroid-binding globulin | 2 | 2.65 | 3.26E−02 | 4 | 3.35 | 1.21E−01 | [80] |
Q5T200 | Zinc finger CCCH domain-containing protein 13 | 3 | 8.07 | 4.18E−03 | 3 | 5.71 | 1.35E−01 |  |
P18428 | Lipopolysaccharide-binding protein | 5 | 0.29 | 7.55E−04 | 8 | 0.43 | 1.71E−01 | [81] |
P98164 | Low-density lipoprotein receptor-related protein 2 | 5 | 4.00 | 1.25E−02 | 10 | 3.92 | 1.71E−01 | [58]  |
Q5T011 | Protein SZT2 | 2 | 0.33 | 1.86E−02 | 3 | 0.37 | 1.71E−01 |  |
P04114 | Apolipoprotein B-100 | 68 | 2.47 | 3.26E−02 | 135 | 2.16 | 1.71E−01 | |
Q9NS86 | LanC-like protein 2 | 3 | 2.54 | 4.64E−02 | 3 | 2.76 | 1.71E−01 |  |
Q9H7L9 | Sin3 histone deacetylase corepressor complex component SDS3 | 2 | 4.70 | 1.84E−02 | 4 | 2.50 | 2.00E−01 |  |
O60884 | DnaJ homolog subfamily A member 2 | 2 | 6.36 | 2.67E−03 | 2 | 2.21 | 2.31E−01 |  |
Q5T481 | RNA-binding protein 20 | 4 | 4.84 | 9.84E−04 | 4 | 4.61 | 2.35E−01 | |
Q5VZL5 | Zinc finger MYM-type protein 4 | 2 | 0.36 | 5.30E−03 | 2 | 0.38 | 2.62E−01 |  |
O15553 | Pyrin | 2 | 11.75 | 1.72E−03 | 2 | 2.65 | 2.74E−01 | |
Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | 2 | 0.15 | 7.33E−03 | 3 | 0.49 | 3.11E−01 |  |
Q8N436 | Inactive carboxypeptidase-like protein X2 | 2 | 0.46 | 1.84E−02 | 3 | 0.37 | 3.11E−01 |  |
Q14767 | Latent-transforming growth factor beta-binding protein 2 | 4 | 0.28 | 7.58E−04 | 6 | 0.43 | 3.15E−01 | [84] |
Q8IWB6 | Inactive serine/threonine–protein kinase TEX14 | 2 | 4.64 | 3.84E−02 | 4 | 2.43 | 3.60E−01 |  |
Q5T9S5 | Coiled-coil domain-containing protein 18 | 2 | 0.37 | 2.01E−02 | 3 | 0.25 | 3.89E−01 |  |
Q8N163 | Cell cycle and apoptosis regulator protein 2 | 2 | 0.21 | 3.51E−02 | 3 | 0.17 | 3.89E−01 |  |
Q9GZU1 | Mucolipin-1 | 2 | 0.35 | 1.46E−02 | 3 | 0.48 | 4.10E−01 |  |
O43301 | Heat shock 70 kDa protein 12A | 2 | 3.16 | 1.68E−02 | 2 | 3.91 | 4.11E−01 | [85] |
A6NES4 | Maestro heat-like repeat-containing protein family member 2A | 2 | 0.28 | 7.55E−04 | 3 | 0.24 | 6.48E−01 |  |