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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Molecular and histological effects of MR-guided pulsed focused ultrasound to the rat heart

Fig. 6

The effect of pFUS on EBD extravasation. a Gross examination shows significant EBD extravasation into the extracellular spaces, specifically in the region of pFUS treatment. b Macroscopic examination of tissue sections revealed that significant amount of EBD extravasated into sonicated myocardium. c fIHC analysis confirmed that the greatest amount of EBD was observed in sonicated region. Scale bar = 4 mm. d, e Show higher magnifications of pFUS untreated and treated regions. Scale bar = 100 µm. Blue/red represent DAPI/EBD respectively

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