Fig. 2

EZH2 copy number levels and corresponding protein levels in cell lines, PDX models and patient tissues. a, c qRT-PCR analysis was used to detect EZH2 copy number levels in four BRAF-mutated cell lines and PDX models. b, d Immunoblots was conducted to determine the protein levels of EZH2 in four BRAF-mutated cell lines and PDX models. GAPDH serves as loading control. e Representative images from EZH2 staining of the same samples described in Fig. 1a magnification, ×200. Scale bars, 100 um