Table 1 Clinical and echocardiographic characteristics of the patients included in the microarray
From: Specific circulating microRNA signature of bicuspid aortic valve disease
Control | BAV | BAVdil | p | |
|---|---|---|---|---|
Age (years) | 41 ± 4 | 33 ± 3 | 41 ± 4 | 0.177 |
Sex (male/female) | (6/0) | (6/0) | (6/0) | 1.000 |
Body weight (kg) | 74.2 ± 2.2 | 75.0 ± 4.2 | 79.0 ± 5.7 | 0.743 |
Hypertension | 0 (0%) | 0 (0%) | 0 (0%) | 1.000 |
Hypercholesterolemia | 0 (0%) | 0 (0%) | 2 (22.2%) | 0.162 |
Smoker | 1 (20.0%) | 2 (22.2%) | 3 (33.3%) | 0.814 |
Aortic stenosis (mean gradient ≥20 mm Hg) | 0 (0%) | 0 (0%) | 0 (0%) | 1.00 |
Aortic regurgitation (≥II) | 0 (0%) | 3 (33.3%) | 6 (66.7%) | 0.031* |
Aortic valve gradient (mean, mm Hg) | 3.75 ± 0.3 | 4.6 ± 0.8 | 7.22 ± 1.6 | 0.190 |
Left ventricle diastolic diameter (mm) | 51.67 ± 1.5 | 50.75 ± 1.0 | 55.11 ± 1.3 | 0.050 |
Left ventricle systolic diameter (mm) | 32.33 ± 0.9 | 31.88 ± 2.7 | 33.78 ± 1.4 | 0.484 |
Left ventricular ejection fraction (%) | 74.40 ± 3.2 | 71.25 ± 1.2 | 71.33 ± 2.6 | 0.641 |
Ascending aorta diameter (mm/m2) | 15.05 ± 0.4 | 15.74 ± 0.7 | 20.71 ± 1.1 | 0.001** |