Table 2 Summary of physical features and diagnostic symptom profile for the CFS/ME cohort investigated for cytokine and activin/follistatin variation
Measurement | Median (range) | |
|---|---|---|
CFS/ME cohort | Healthy control cohort | |
Height (cm) | 165.0 (122–188) | 171.5 (153–187) |
Weight (kg) | 60.0 (52–124) | 66.0 (51–98) |
BMI | 22.2 (18.9–47.2) | 21.9 (19.6–32.1) |
Blood pressure | ||
Systolic (mmHg) | 120.0 (102–168) | 121.5 (107–140) |
Diastolic (mmHg) | 80.0 (65–104) | 74.0 (55–90) |
Pulse rate (bpm) | 72.0 (51–102) | 60.0 (43–89) |
Epworth sleep scale | 6.0 (0–20) | 4.0 (0–15) |
Canadian criteria symptoms (percentage) | CFS/ME cohort | |
|---|---|---|
Reported by 100% of study participants | Fatigue ≥6 months | Post-exertional fatigue |
Activity limited | Stress with activity | |
Unrefreshing sleep | Reduced concentration | |
Impaired thinking + speech | Orthostatic intolerance | |
Vertigo | Food intolerance | |
Reported by ~50% of study participants | Gut axis (constipation, indigestion, diarrhoea) | Sleep (difficulty to wake, sleeping during day) |
New allergies | Sighing breaths | |
Arrhythmia | Confusion | |
Smell sensitivity | ||
Reported by ≤10% of study participants | Migraine headache | Sensitivity to touch |
High heart rate upright | Pain frequency | |