Table 1 Patient’s demographics and specimen characteristics from the two cohorts

Cases

86 (100)

102 (100)

 Gender

0.974

  Male

55 (64.0)

65 (63.7)

  Female

31 (36.0)

37 (36.3)

 Age (years)

70.0 (63.0–79.0)

65.5 (59.0–72.0)

0.0635

Tumor characteristics

 Size (cm)

3.0 (1.7–4.5)

2.5 (1.1–3.7)

0.992

 Location

0.090

  Right colon

39 (45.3)

51 (50.0)

  Flexures/transverse

1 (1.2)

7 (6.9)

  Left colon

46 (53.5)

44 (43.1)

 Gross configuration

0.821

  Polypoid

57 (66.3)

66 (64.7)

  Ulcerated

29 (33.7)

36 (35.3)

 Grade

<0.001

  High

49 (57.0)

26 (25.5)

  Low

37 (43.0)

76 (74.5)

 Type of tumor

0.118

  Adenoma

6 (7.0)

8 (7.8)

  Carcinoma in situ

6 (7.0)

17 (16.7)

  Adenocarcinoma

74 (86.0)

77 (75.5)

 Budding

0.650

  Absence

13 (17.6)

14 (18.7)

  Low grade

47 (63.5)

51 (68.0)

  High grade

14 (18.9)

10 (13.3)

 Vascular invasion

0.045

  No

65 (75.6)

91 (89.2)

  Yes

21 (24.4)

11 (10.8)

 Perineural invasion

0.013

  No

76 (88.4)

98 (96.1)

  Yes

10 (11.6)

4 (3.9)

 Tumor deposits

0.165

  No

81 (94.2)

100 (98.0)

  Yes

5 (5.8)

2 (2.0)

 pT

0.004

  pT0

6 (7.0)

8 (7.8)

  pTis

6 (7.0)

17 (16.7)

  pT1

9 (10.4)

26 (25.6)

  pT2

16 (18.6)

19 (18.6)

  pT3

32 (37.2)

24 (23.5)

  pT4a

17 (19.8)

8 (7.8)

Lymph nodes

 Total LN

1992 (100)

1828 (100)

  Fresh LN

1757 (88.2)

1449 (79.3)

  FFPE LN

235 (11.8)

379 (20.7)