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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Changes in ceftriaxone pharmacokinetics/pharmacodynamics during the early phase of sepsis: a prospective, experimental study in the rat

Fig. 3

a CTX urinary concentration (mg/L) at the end of the experimental time (6 h). A significant increased quantity of bound-CTX was present in the urine of septic rats (553.53 vs 149.27 mg/L; *p < 0.05 CLP vs SHAM). b Total urinary loss of CTX (mg) at the end of the experimental time (6 h); the quantity was the product of the 6 h urinary volume and CTX concentration. Due to a reduced urinary output, CTX total loss was reduced in septic rats (1.85 vs 3.34 mg *p < 0.05)

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