Table 2 Intragroup comparison of Fabry patients
From: Increased urinary CD80 excretion and podocyturia in Fabry disease
Variables | No ERT (n: 23) | ERT (n: 22) | p value |
|---|---|---|---|
Age (years) | 19 (11–75) | 38.5 (17–86) | 0.02 |
Gender (males) | 4 (14 %) | 14 (64 %) | 0.01 |
Time on ERT (months) | 0 | 42 (34–50) | <0.0001 |
eGFR (ml/min/1.73 m2) | 141 (60–165) | 120.5 (21–148) | 0.03 |
UPCR (g/g) | 0.06 (0.02–2.35) | 0.11 (0.02–5.68) | 0.04 |
Podocyturia/Cr (cells/g) | 34 (4–439) | 24 (0–107) | 0.45 |
uCD80/Cr (ng/g) | 40 (0–235) | 47 (0–2966) | 0.7 |
Mutations | D33G, L415P, R227X, A292T, N34D, C801, C326, C647A, C281, G640C, C1244T | D33G, L415P, R227X, A292T, N34D, D264Y, D155H, L180F |