Immunological profiling of patients with ulcerative colitis leads to identification of two inflammatory conditions and CD1a as a disease marker

Table 1 Cellular markers used in phenotyping of UC patients

Marker	Definition	References
CD19+ CD27+ IgD+	Unswitched memory B-cell	[30]
CD19+ CD27+ IgD−	Switched memory B-cell	[30]
CD19+ CD38+	Plasma cell	[30]
CD4+ CD25+	Activated CD4+ T-, regulatory T cells, Th2 cells	[31, 32]
CD14+	MC	[33]
CD14+ CD80+ CD86+	MC, mature	[33–35]
CD14+ CCR2+	MC, tissue penetrating, inflammatory	[36]
CD14+ TSLPR+	MC, expressing TSLPR
CD14+ CD64+	M1MC	[37]
CD14+ CD163+	M2 MC, scavenging cells	[35]
CD14+ CD1a	MC CD1a expressing
CD11b+	cDC1	[33]
CD11b+ CD80/86+	cDC1, mature
CD11b+ CD1a+	cDC1 CD1a expressing
CD11b+ TSLPR+	cDC1 TSLPR expressing
CD3+ CD56+	NK T-cell	[38]
CD3− CD56+	NK cell
CD3− CD56−, CRTH2+ CD127+	ILC2	[39–41]

MC monocyte, NK natural killer cell, TSLPR thymic stromal lymphopoietin protein, cDC conventional dendritic cell

ISSN: 1479-5876