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Table 2 Mean ± SD of protein concentrations of TGF-β1, IL-6, IL-10, IL-22 and total MMP9 in liver tissue homogenates by ELISA

From: The fibrolytic potentials of vitamin D and thymoquinone remedial therapies: insights from liver fibrosis established by CCl4 in rats

 

NC group

S-PC group

L-PC group

TQ group

VitD group

VitD/TQ group

TGF-β1 (pg/ml)

569.6 ± 97.8

988.4 ± 93.3a

1394.7 ± 101.4a,b

875.2 ± 76.7a,b,c

705.6 ± 56.3a,b,c,d

600.2 ± 78.7b,c,d,e

IL-6 (pg/ml)

663.9 ± 76.5

1721.2 ± 325.3a

1980.4 ± 233.4a

717.4 ± 110b,c

672.3 ± 94.9b,c

457.4 ± 121a,b,c,d,e

IL-10 (pg/ml)

479.06 ± 21.9

222.7 ± 53.8a

121.5 ± 26.6a,b

206.9 ± 23.3a,c

237.1 ± 25.7a,c

323.2 ± 33.5a,b,c,d,e

IL-22 (pg/ml)

379.7 ± 48.4

744.9 ± 61.7a

963.8 ± 102a,b

649.8 ± 52.3a,b,c

663.6 ± 47.4a,c

452.5 ± 38.9a,b,c,d,e

MMP-9 (ng/ml)

4.1 ± 0.13

3.4 ± 0.31a

2.6 ± 0.52a,b

3.7 ± 0.36a,c

3.9 ± 0.17a,b,c

4.52 ± 0.34a,b,c,d,e

  1. aP < 0.05 compared with NC group
  2. bP < 0.05 compared with S-PC group
  3. cP < 0.05 compared with L-PC group
  4. dP < 0.05 compared with TQ group
  5. eP < 0.05 compared with VitD group