Fig. 5From: Repurposing of approved cardiovascular drugsEffects of statins on mevalonate pathway in tumor cells. Downstream products in the mevalonate pathway such as geranylgeranyl pyrophosphate (GGPP) and farnesyl pyrophosphate (FPP) are substrates in protein prenylation. By inhibiting the formation of GGPP and FPP, statins exert anti-proliferatic activity in tumor cellsBack to article page