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Table 1 Patient characteristics (N = 132)

From: Fibrinogen consumption is related to intracranial clot burden in acute ischemic stroke: a retrospective hyperdense artery study

Characteristic

Values

Demographics

 Age (years)

77 (19–97)

 Men

55 (41.7)

Medical history

 Prior stroke/TIA

17 (12.9)

 Atrial fibrillation

67 (50.8)

 Peripheral artery disease

11 (8.3)

 Carotid stenosis >50 %

15 (11.4)

 Arterial hypertension

93 (70.5)

 Diabetes mellitus

21 (15.9)

 Chronic heart failure

18 (13.6)

 Use of antiplatelets

41 (31.1)

 Use of anticoagulants

12 (9.1)

 Use of any antithrombotic

53 (40.2)

Stroke type by TOAST

 Cardioembolic

77 (58.3)

 Unknown

37 (28.0)

 Large artery atherosclerosis

15 (11.4)

 Other

3 (2.3)

Clinical presentation

 NIHSS (points)

16 (0–32)

 Serum glucose (mmol/L)

6.7 (3.1–12.9)

 HbA1c (mmol/L)

5.5 (4.3-8.5)

 Fibrinogen (μmol/L)

10.5 (3.1–24.3)

 C-reactive protein (mg/L)

0.45 (0.01–21.2)

Acute treatment

 Thrombolysis (rt-PA)

79 (59.9)

 Thrombectomy

58 (43.9)

Thrombectomy outcome (TICI)

 No perfusion (0)

10/58 (17.2)

 Penetration, no distal filling (1)

3/58 (5.2)

 Perfusion, <50 % distal filling (2a)

3/58 (5.2)

 Inadequate (0–2a total)

16/58 (27.6)

 Perfusion, >50 % distal filling (2b)

15/58 (25.9)

 Full perfusion (3)

27/58 (46.5)

 Adequate (2b–3 total)

42/58 (72.4)

Imaging particulars

 Symptoms to image (min)

116 (17–350)

 Affected vessel

  Middle cerebral artery proximal

83 (62.9)

  Middle cerebral artery distal

30 (26.6)

  Basilar artery

8 (6.1)

  Vertebral artery

6 (4.6)

  Posterior cerebral artery

3 (2.3)

  Anterior cerebral artery

1 (0.8)

  Other vessel

1 (0.8)

 Clot area (mm2)

25.2 (2.5–211)

 Final infarct volume (mm3)

37.3 (0–518)

 Control image finding

  Infarction

88 (66.7)

  Hemorrhagic infarction

20 (15.2)

  Resolution (infarct volume = 0)

11 (8.3)

  None

13 (9.9)

Clinical outcome

 In-hospital mortality

26 (19.7)

 NIHSS at discharge (points)

6 (0–30)

  1. Data are median (range) or absolute numbers (percentage)
  2. HbA1c glycated hemoglobin, NIHSS National Institutes of Health Stroke Scale, rt-PA recombinant human tissue plasminogen activator, TIA transitory ischemic attack, TICI thrombolysis in cerebral infarction grading, TOAST Trial of Org 10172 in Acute Stroke Treatment