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Table 2 Serum biochemical parameters related to BC safety

From: Integrative analysis of metabolome and gut microbiota in diet-induced hyperlipidemic rats treated with berberine compounds

Items

Chow diet rats (n = 10)

HFD rats (n = 10)

BC treated rats (n = 10)

ALT

20.3 ± 2.8

42.2 ± 12.6***

38.0 ± 13.4***

AST

109.2 ± 6.6

151.2 ± 41.1*

107.3 ± 13.4#

TBIL

0.7 ± 0.1

0.6 ± 0.5

0.6 ± 0.2

TBA

4.5 ± 1.4

5.4 ± 1.9

7.1 ± 3.4

  1. Data are presented as Mean ± SD
  2. * P < 0.05, *** P < 0.001 compared with chow diet group; #   P < 0.05, compared with HFD group