Skip to main content
Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Integrative analysis of metabolome and gut microbiota in diet-induced hyperlipidemic rats treated with berberine compounds

Fig. 5

The metabolic profiles in feces. The HFD induced hyperlipidemic rats were treated with or without BC for 4-week, feces were collected, and metabolomics analysis was made by GC/MS. a PCA score plots of the feces from BC treated group and untreated group; b scores plots of PLS-DA between untreated group and BC treated group; c Pearson’s correlations of the quantities of the 67 metabolites determined from the feces samples; d heat map showing the FC of 19 metabolites, shades of green represent FC decrease while red represent FC increase; e simplified draft illustrating perturbed pathways involved; f differential metabolites between the groups in tyrosine metabolism; g differential metabolites between the groups in β-alanine metabolism; h differential metabolites between the groups in arginine and proline metabolism; i differential metabolites between the groups in secondary bile acid biosynthesis. Values were showed as mean peak intensities ± SEM. *P < 0.05, **P < 0.01 and ***P < 0.001, compared with untreated (HFD) group

Back to article page