Fig. 2

miR-145 mediates the anti-proliferative effect of aspirin in TNF-α treated VSMCs. VSMCs in different groups were treated as previously described. a The proliferation of VSMCs was determined by EdU; b statistical analyses of VSMCs proliferation; c the level of Calponin expression was determined by real-time PCR, and values are presented as the mean ± SD; n = 3. Experiments were performed 3 times with similar results. *P < 0.05, **P < 0.01 vs DMSO, ^##P < 0.01 vs TNF-α, ^&&P < 0.01 vs +ASA