Fig. 2

Functional parameters in the murine MI model. Cardiac parameters were assessed 4 weeks after permanent ligation of the LAD. Three groups have been compared: sham (n = 10), MI-placebo (n = 15), MI-SAR1 (n = 10). Results are expressed as mean ± SEM. Differences significant at p < 0.05 are marked with an asterisk (*). LVESV left ventricular end-systolic volume, LVEDV left ventricular end-diastolic volume, LVEDP left ventricular end-diastolic pressure, CO cardiac output, EF ejection fraction, SV stroke volume, MAP mean arterial pressure, HR heart rate, dP/dt peak positive or negative first derivative of LV pressure, BNP plasma brain natriuretic peptide