Fig. 1
IHC analysis of PFN2 protein in adjacent normal tissues, precancerous lesions, and ESCC tissues from Chinese Han population. Typical PFN2 immunostaining in a NEE, b LGIN and HGIN, and c ESCC in the Chinese Han population (top image magnification ×40; middle and bottom image magnification ×200; bottom image stands for negative control) PFN2 staining was located to the nuclei/cytoplasm. d (Box plot) Range of PFN2 immunoreactivity score in NEE, LGIN, HGIN, and ESCC tissues (**P < 0.01, ***P < 0.001). e (Bar chart) Distribution ratio of NEE, LGIN, HGIN and ESCC tissues in four-level score (0–1, 2–3, 4–8, and 9–12) of PFN2 expression