Table 2 Allele and genotype frequencies at the CLTA-4 loci in 152 donors
Polymorphism | All donors (%) | Donors in ALL (%) | Donors in AML (%) |
|---|---|---|---|
No of donors | 152 | 83 | 69 |
−1661 (rs4553808) | |||
 AA | 109 (71.7) | 61 (73.5) | 48 (69.6) |
 AG | 36 (23.7) | 18 (21.7) | 18 (26.1) |
 GG | 7 (4.6) | 4 (4.8) | 3 (4.3) |
 A allele | 254 (83.6) | 140 (84.3) | 114 (82.6) |
 G allele | 50 (16.4) | 26 (15.7) | 24 (17.4) |
 HWE Pa | 0.09 | 0.10 | 0.44 |
−318 (rs5742909) | |||
 CC | 109 (71.7) | 61 (73.5) | 48 (69.6) |
 TC | 36 (23.7) | 18 (21.7) | 18 (26.1) |
 TT | 7 (4.6) | 4 (4.8) | 3 (4.3) |
 C allele | 254 (83.6) | 140 (84.3) | 114 (82.6) |
 T allele | 50 (16.4) | 26 (15.7) | 24 (17.4) |
 HWE Pa | 0.09 | 0.10 | 0.44 |
CT60 (rs3087243) | |||
 GG | 96 (63.2) | 51 (61.5) | 45 (65.2) |
 AG | 53 (34.9) | 30 (36.1) | 23 (33.3) |
 AA | 3 (1.9) | 2 (2.4) | 1 (1.5) |
 G allele | 245 (80.6) | 132 (79.5) | 113 (81.9) |
 A allele | 59 (19.4) | 34 (20.5) | 25 (18.1) |
 HWE Pa | 0.16 | 0.32 | 0.30 |
+49 (rs231775) | |||
 GG | 59 (38.8) | 31 (37.3) | 28 (40.6) |
 AG | 77 (50.7) | 44 (53.0) | 33 (47.8) |
 AA | 16 (10.5) | 8 (9.7) | 8 (11.6) |
 G allele | 195 (64.1) | 106 (63.9) | 89 (64.5) |
 A allele | 109 (35.9) | 60 (36.1) | 49 (35.5) |
 HWE Pa | 0.21 | 0.18 | 0.71 |