Table 1 Biochemical effects of MPTP administration animal model by Hericium erinaceus mycelium
Neurotoxic effects of the striatum | |||||
|---|---|---|---|---|---|
|  | Control (n = 6) | MPTP (n = 6) | MPTP + HEM 5.38 mg/day (n = 6) | MPTP + HEM 10.76 mg/day (n = 6) | MPTP + HEM 21.52 mg/day (n = 6) |
Dopamine (ng/ml) | 3.6 ± 0.15 | 1.7 ± 0.1 | 3.1 ± 0.1* | 3.8 ± 0.1* | 4.1 ± 0.1* |
NGF (ng/ml) | 2.8 ± 0.5 | 1.2 ± 0.1 | 1.9 ± 0.3* | 2.3 ± 0.4* | 2.7 ± 0.3* |
GSH/mg | 140 ± 11 | 62 ± 6 | 94 ± 8 | 134 ± 10 | 138 ± 8* |